In a new study, scientists have identified a small molecule candidate drug that triggers the formation of left-handed Z-DNA in cells that in turn activates a highly immunogenic programmed pathway of ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

These viruses use a unique genetic alphabet not found anywhere else on the planet. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. The blueprint ...

Plants and animals have genomes made of four nucleotide bases, adenine (A), thymine (T), cytosine (C), and guanine (G). But there's another genetic 'letter' that's been identified; in 1977 a virus ...

The normal (B-form) DNA will switch to left-handed (Z-form) DNA when it is physically twisted, or when a lot of salt is added to the solution. Researchers at the University of Luxembourg were able to ...

In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on ...