Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...
Mitochondria produce most of the cellular ATP by the process of oxidative phosphorylation (OXPHOS) and generate most of the endogenous oxygen radicals as a toxic by-product. In addition, mitochondria ...
Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...
In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 33 (Aug. 15, 2006), pp. 12311-12316 (6 pages) We have developed methods for using DNA array technology to ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
In today's issue of Science, researchers at the Whitehead Institute and Corning Inc. describe a new microarray technique that can decipher the function of master switches in a cell by identifying the ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback